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Looking to identify new strategies to prevent breast cancer recurrence, a research team led by Subhamoy Dasgupta, PhD, Assistant Professor of Oncology in the Department of Cell Stress Biology at Roswell Park Comprehensive Cancer Center, has identified two key proteins involved in glucose metabolism that could be targeted to prevent breast cancer metastasis and recurrence. The team’s findings were published today in the journal Nature.

Rapid growth and proliferation are hallmarks of cancer cells, which require a large amount of glucose to meet their energy needs. Because the majority of advanced breast tumors are notably dependent on glucose metabolism, strategies that alter the metabolic pathways of cancer cells can be used to improve outcomes and prevent metastasis or recurrence in patients with breast cancer.

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